产品货号：
Z23670
中文名称：
PHAP III/ANP32E抗体
英文名称：
Anti-PHAP III/ANP32E Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PHAP III/ANP32E Antibody |
| 指标别名 | LANPL,LANP-L,Acidic leucine-rich nuclear phosphoprotein 32 family member E,LANP-like protein |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | ANP32E |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | PHAP III antibody was raised with a synthetic peptide corresponding to amino acids close to carboxy terminus of human PHAP III.The immunogen is located within amino acids 200 - 250 of PHAP III. |
| 计算分子量 | 31kDa |
| 成分 | PHAP III Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | PHAP III Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | PHAP III antibody can be stored at 4℃ up to one year.Antibodies should not be exposed to prolonged high temperatures. |
| 背景资料 | Apoptosis is related to many diseases and development.Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators.Cytochrome c,after released from mitochondria,binds to Apaf-1,which forms an apoptosome that in turn binds to and activate procaspase-9.Activated caspase-9 cleaves and activates the effector caspases (caspase-3,-6 and -7),which are responsible for the proteolytic cleavage of many key proteins in apoptosis.The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis.PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway.PHAP was also shown to oppose both Ras- and Myc-medicated cell transformation. |
| Uniprot ID | Q9BTT0 |
| 基因名全称 | Acidic (leucine-rich) nuclear phosphoprotein 32 family,member E |
| 蛋白名全称 | Acidic (leucine-rich) nuclear phosphoprotein 32 family,member E |
| 推荐稀释比 | PHAP III antibody can be used for detection of PHAP III by Western blot at 1μg/mL.A band at approximately 35kDa can be detected.Antibody can also be used for immunohistochemistry starting at 2μg/mL.For immunofluorescence start at 10μg/mL.Antibody validated:Western Blot in human and rat samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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